In the formula editor, this works nicely,
P_{ {RS}} = left( matrix{ p_AA # p_AG # p_AC # p_AU ## p_GA # p sub {“GG”} # p_GC # p_GU ## p_CA # p_CG # p_CC # p_CU ## p_UA # p_UG # p_UC # p_UU } right)
except I would like the subscript RS to be in the Libre sans style and not italic, and I couldn’t figure out how to make that happen. Is it possible?