Is there some way to reset Calc so I can click on a hyperlinks without having to use the CTRL key?
Deselect:
Tools menu > Options > LibreOffice > Security :: Security Options and Warnings :: Options > Security Options :: Ctrl-click required to follow hyperlinks
Calc creates a border around the hyperlink that is the same color of the cell.
Probably you mean the Field Shade?
Tools menu > Options > LibreOffice > Application Colors > Text Document :: Field shadings
Choose another color or deselect. Please notice: This alteration has an impact on other program tools, too (eg Writer).