Cannot open LO

It states “either another instance of LO is accessing my personel settings or personel settings are locked”

Hello,

check procedure in answer Opening Libre office documents.

Note:
If you additionally face a crash of Windows, please check March 15, 2021—KB5001567 (OS Builds 19041.868 and 19042.868) Out-of-band which fixes a Windows Update problem mentioned in bug tdf#140952.

Hope that helps.