Write Error: the file could not be written

Windows 10 update yesterday and today I cannot save the entire spreadsheet file. I can copy and save a page at a time from a 300+ line entry but only in XLS. I don’t have ransomware or anti-virus except Webroot which I can’t control or disable. I have checked properties/permissions and all is set up to give me total control. Still trying, I also get message “insufficient user rights” that I have had before and changed in expert-config, uselocking to false. It is still in false so this didn’t help again. So not being able to save is the second time this has happened after a Windows update. I see another person has had this problem 27 days ago but they could not discern anything they did which enabled saving to start happening again. I am not that computer literate. Using Libreoffice 7.6.2.1. My apologies for posting same topic but I can’t see any other appropriate action that might provoke some assistance.

See your administrator to allow soffice.bin, see for how Blocking or Allowing Files

Thank you…I will attempt