Am getting General input/output error while accessing C:\Users\****\Documents\*****.ods. How do I fix? Cannot save and really need. HELP?

Am attempting to update current LibreOffice document. Allows me to pull up, and edit. However, when I attempt to save, get General input/output error while accessing C:\Users*\Documents************.ods. **** is my name, *********** is name of my document. How do I fix? I am not a whiz at computers, need easy-to-understand fix. Thank you so much.

Please see here.